Myelin oligodendrocyte glycoprotein antibody disease


Disease modifying treatment available:
Time critical diagnosis and management:
Lateralising:


Synonyms

  • MOG antibody disease
  • MOGAD


Definition

None




Aetiology

None




Clinical features


None

Myelin oligodendrocyte glycoprotein antibody disease may cause the following:





Investigations


Anti-MOG antibodies in the serum.

None


Laboratory Investigation Result

Treatment


Acute management of relapses utilises steroids, intravenous immunoglobulin and plasma exchange. Long term immunosuppression to reduce relapse rate is often achieved with rituximab, cyclophosphamide, azathioprine, MMF or tocilizumab.





Research


Open questions

None